▎ 摘　　要

A generalized strategy for developing a hybrid two-dimensional nanostructured dual T-1-T-2 MRI contrast agent (CA), by co-loading graphene oxide with both Mn-doped Fe3O4 (T-2 agent) and MnO (T-1 agent) magnetic nanoparticles, is reported. Typical T-1/T-2 signal quenching, due to magnetic coupling, was not observed because of the fair T-1 CA separation distance from the T2 CA on the graphene oxide. The resultant two-dimensional nanostructured MRI CA complements the existing dual T-1-T-2 MRI CA libraries.