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  • 文献标题:   Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment
  • 文献类型:   Review
  • 作　　者:   FADEEL B, BUSSY C, MERINO S, VAZQUEZ E, FLAHAUT E, MOUCHET F, EVARISTE L, GAUTHIER L, KOIVISTO AJ, VOGEL U, MARTIN C, DELOGU LG, BUERKITHURNHERR T, WICK P, BELOINSAINTPIERRE D, HISCHIER R, PELIN M, CARNIEL FC, TRETIACH M, CESCA F, BENFENATI F, SCAINI D, BALLERINI L, KOSTARELOS K, PRATO M, BIANCO A
  • 作者关键词:   carbon nanomaterial, graphene, hazard, exposure, life cycle assessment, environment, safety, toxicity
  • 出版物名称:   ACS NANO
  • ISSN:   1936-0851 EI 1936-086X
  • 通讯作者地址:   Karolinska Inst
  • 被引频次:   35
  • DOI:   10.1021/acsnano.8b04758
  • 出版年:   2018

▎ 摘　　要

Graphene and its derivatives are heralded as "miracle" materials with manifold applications in different sectors of society from electronics to energy storage to medicine. The increasing exploitation of graphene-based materials (GBMs) necessitates a comprehensive evaluation of the potential impact of these materials on human health and the environment. Here, we discuss synthesis and characterization of GBMs as well as human and environmental hazard assessment of GBMs using in vitro and in vivo model systems with the aim to understand the properties that underlie the biological effects of these materials; not all GBMs are alike, and it is essential that we disentangle the structure-activity relationships for this class of materials.