• 文献标题:   Amyloid-graphene oxide as immobilization platform of Au nanocatalysts and enzymes for improved glucose-sensing activity
  • 文献类型:   Article
  • 作  者:   WU XC, LI MJ, LI ZH, LV LL, ZHANG Y, LI CX
  • 作者关键词:   amyloid nanofibril, graphene oxide, au nanoparticle, biocompatible immobilization platform, biosensing
  • 出版物名称:   JOURNAL OF COLLOID INTERFACE SCIENCE
  • ISSN:   0021-9797 EI 1095-7103
  • 通讯作者地址:   Chinese Acad Sci
  • 被引频次:   13
  • DOI:   10.1016/j.jcis.2016.11.058
  • 出版年:   2017

▎ 摘  要

Two-dimensional GO nanosheets and one-dimensional lysozyme nanofibrils were hybridized through electrostatic interaction to get a novel amyloid-GO composite, which promised a biocompatible immobilization platform for Au nanocatalysts as well as enzymes. The immobilization platform could load a large and tunable amount of Au NPs while maintaining their high catalytic activity. The immobilized catalysts showed high electrochemical behaviors, being ideal as glucose sensing systems. Furthermore, enzymes could also be immobilized on the residual bare surfaces of amyloid-GO, and served by a colorimetric method for a sensitive and selective analytical glucose-detecting platform. The introduction of amyloid fibrils with super large aspect ratios (>10(3)) on GO nanosheets offers an unprecedented possibility of designing and developing novel biomimetic catalysts for broad applications in biotechnology. (C) 2016 Elsevier Inc. All rights reserved.