• 文献标题:   Poly(Vinyl Alcohol) Enhances Acetylation of Ascorbic Acid in Superparamagnetic Graphene Oxide Nanoparticles Ultrasonically Complexed with Acetylsalicylic Acid
  • 文献类型:   Article
  • 作  者:   TKACH A, FIADOSENKA U, BURKO A, BANDARENKA H, MATSUKOVICH A, KREKOTEN N, TABULINA L, LABUNOV V, RADZIUK D
  • 作者关键词:   polymer, graphene, iron oxide, nanoparticle, acetylsalicylic acid
  • 出版物名称:   ACS APPLIED POLYMER MATERIALS
  • ISSN:   2637-6105
  • 通讯作者地址:   Belarusian State Univ Informat Radioelect
  • 被引频次:   0
  • DOI:   10.1021/acsapm.0c00648
  • 出版年:   2020

▎ 摘  要

A single-step ultrasonic method (20 kHz) is demonstrated for the formation of acetylsalicylic acid-Fe3O4-graphene oxide nanocomposites (similar to 80 nm) in aqueous solution. The electronic molecular structure of these nanocomposites is stable in acidic or basic aqueous medium. Coating of these nanocomposites with poly(vinyl alcohol) (PVA) occurs through increased binding with drug, magnetite, Fe(II)-C-O and carbonaceous network of graphene oxide. PVA-coated-acetylsalicylic acid-Fe3O4-GO nanocomposites substantially improve acetylation of pristine ascorbic acid than free unmodified drug or uncoated acetylsalicylic acid-Fe3O4-GO nanoparticles because of enhanced electron density through the presence of magnetite and graphene oxide, and specific binding of PVA with drug and ascorbic acid.