• 文献标题:   Blue fluorescent graphene oxide hybrid: Synthesis, characterization, and application as a drug delivery system
  • 文献类型:   Article
  • 作  者:   HASHEMI H, NAMAZI H
  • 作者关键词:   graphene oxide, blue fluorescent, drug delivery, cell viability
  • 出版物名称:   JOURNAL OF DRUG DELIVERY SCIENCE TECHNOLOGY
  • ISSN:   1773-2247
  • 通讯作者地址:   Univ Tabriz
  • 被引频次:   1
  • DOI:   10.1016/j.jddst.2018.10.010
  • 出版年:   2018

▎ 摘  要

Aminated TriPhenylAmine (A-TPA) was synthesized, and attached to the 1, 3, 5 Benzene Tricarbonyl trichloride (BT) in order to make an electron rich molecule (A-TPA-BT) and, be used for functionalization of the Graphene Oxide (GO) surface. A comprehensive study about the properties of the functionalized GO was carried out and completed by detailed characterization techniques such as Fourier transformed infrared spectroscopy (FT-IR); UV-Vis absorption spectroscopy; Scanning Electron Microscope (SEM/EDS); X-Ray photoelectron spectroscopy (XPS); Fluorescence spectroscopy and X-ray Diffraction spectroscopy (XRD). The synthesized A-TPA-BT compound displayed a red emission at 632 nm. However, after functionalization, a blue photoluminescence was detected at 468 nm. The covalent connection of the A-TPA-BT moieties onto the GO surface, create a new electronic energy state and simultaneously distort the bandgap of the GO and led to observation of 164 nm blue shift of luminescence. Indeed, the cytotoxicity measurement of the hybrid against human breast cancer cells (T47D) was studied.