• 文献标题:   Electrochemical detection of dopamine based on pre-concentration by graphene nanosheets
  • 文献类型:   Article
  • 作  者:   BAGHERZADEH M, HEYDARI M
  • 作者关键词:  
  • 出版物名称:   ANALYST
  • ISSN:   0003-2654 EI 1364-5528
  • 通讯作者地址:   NSTRI
  • 被引频次:   39
  • DOI:   10.1039/c3an01318a
  • 出版年:   2013

▎ 摘  要

Herein, graphene nanosheets (GNS) were synthesized, by a green and facile method based on reduction by glucose, and characterized. Afterwards, a carbon paste electrode (CPE) was modified with GNS by casting and drying GNS on top of the CPE (CPE/GNS). The behavior of the CPE/GNS towards dopamine (DA) and ascorbic acid (AA) was investigated by electrochemical methods and the obtained results showed that the CPE/GNS had adsorbed only DA. Based on this behavior, the DA molecules were pre-concentrated on top of the CPE/GNS, followed by stripping in DA free solution. Subsequent to experimental and instrumental optimization, a calibration curve from 2.0 x 10(-6) to 1.0 x 10(-3) M DA, r(2) = 0.99 (+/- 0.01), with detection limit (DL) = 8.5 x 10(-7) M DA, sensitivity = 15.4 (+/- 0.94) mu A, and RSD = 6.1 was observed in the presence of 1.0 x 10(-3) M AA. Finally, the performance of the CPE/GNS was successfully tested in a pharmaceutical sample. This work provides a promising strategy for DA detection in the presence of biological interferences, e.g. AA, with high sensitivity and simple characteristics.