▎ 摘　　要

Serious health hazards of volatile organic compounds such as methanol and ethanol for living species and their adverse effects on the environment raised a global requirement for developing a portable, precise, and sensitive detection platform capable of simultaneous and differentiable detection of alcohols in aquatic biological and non-biological fluids. Each year, methanol toxicity causes serious healthcare problems and leads to high mortalities in developing countries. Hence, designing and developing a practical nanosensor for diagnostic applications and environmental monitoring is crucial. Herein, we have addressed this demand by fabricating a portable, ultra-sensitive, and precise nanosensor capable of simultaneous and differentiable detection of methanol and ethanol in any aquatic specimen in about 1 min. The nanosensor is composed of the integrated graphene oxide (GO) flakes with the catalytic complex of NiOx and 8-hydroxyquinoline (8HQ) capable of identification of methanol and ethanol with an analytical sensitivity/detection limit of 30.66 pA(pmol/mL)-1.cm-2/6.87 nmol mL-1 and 118.99 pA(p mol/mL)-1.cm-2/1.80 nmol mL-1 using voltammetric assays between the linear range of 0.014 -0.01 pmol mL-1 and 0.83-0.58 pmol mL-1, respectively. The outcome of the assessments exhibited the favorable capability of the prepared nanosensor for precise/prompt detection of alcohols in blood specimens and showed an ideal correlation with the outcome of the gold standard. (c) 2021 Elsevier B.V. All rights reserved.