• 文献标题:   High Value of Proton Relaxivity Achieved by Graphene Oxide-Cobalt Ferrite Nanoparticle Composite: A Potential Contrast Agent in Magnetic Resonance Imaging
  • 文献类型:   Review
  • 作  者:   VENKATESHA N, ASHWINI R, POOJAR P, GEETHANATH S, SRIVASTAVA C
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE
  • ISSN:   0970-4140 EI 0019-4964
  • 通讯作者地址:   Indian Inst Sci
  • 被引频次:   1
  • DOI:  
  • 出版年:   2014

▎ 摘  要

This work investigates the potential of graphene oxide-cobalt ferrite nanoparticle (GO-CoFe2O4) composite as image contrast enhancing material in Magnetic Resonance Imaging (MRI). In the preset work, GO-CoFe2O4 composites were produced by a two-step synthesis process. In the first step, graphene oxide (GO) was synthesized, and in the second step CoFe2O4 nanoparticles were synthesized in a reaction mixture containing GO to yield graphene GO-CoFe2O4 composite. Proton relaxivity value obtained from the composite was 361 mM(-1)s(-1). This value of proton relaxivity is higher than a majority of reported relaxivity values obtained using several ferrite based contrast agents.