▎ 摘　　要

The hierarchical micro/nanoscale layered formation of organic and inorganic components of natural nacre, results in abundant interfacial interactions, providing an inspiration for fabricating bioinspired nanocomposites through constructing the interfacial interactions. Herein, we demonstrated the synergistic interfacial interactions of hydrogen bonding from hydroxypropyl cellulose and ionic bonding from copper ions upon the reduced graphene oxide based bioinspired nanocomposites, which show the integrated tensile strength, toughness and excellent fatigue-resistant property, as well as high electrical conductivity. These extraordinary properties allow this kind of bioinspired nanocomposites to potentially utilize in the fields of aerospace, flexible electronics devices, etc. This study also opens a door for fabricating excellent mechanical performance graphene-based bioinspired nanocomposites via synergistic interfacial interactions in the future.