• 文献标题:   Effects of Lateral Size, Thickness, and Stabilizer Concentration on the Cytotoxicity of Defect-Free Graphene Nanosheets: Implications for Biological Applications
  • 文献类型:   Article, Early Access
  • 作  者:   HU CX, READ O, SHIN YY, CHEN YX, WANG JJ, BOYES M, ZENG NT, PANIGRAHI A, KOSTARELOS K, LARROSA I, VRANIC S, CASIRAGHI C
  • 作者关键词:   graphene, liquidphase exfoliation, pyrene, biocompatibility, atomic force microscopy, sizethickness characterization
  • 出版物名称:   ACS APPLIED NANO MATERIALS
  • ISSN:  
  • 通讯作者地址:  
  • 被引频次:   1
  • DOI:   10.1021/acsanm.2c02403 EA SEP 2022
  • 出版年:   2022

▎ 摘  要

In this work, we apply liquid cascade centrifugation to highly concentrated graphene dispersions produced by liquid phase exfoliation in water with an insoluble bis-pyrene stabilizer to obtain fractions containing nanosheets with different lateral size distributions. The concentration, stability, size, thickness, and the cytotoxicity profile are studied as a function of the initial stabilizer concentration for each fraction. Our results show that there is a critical initial amount of stabilizer (0.4 mg/mL) above which the dispersions show reduced concentration, stability, and biocompatibility, no matter the lateral size of the flakes.