▎ 摘　　要

Recently, Fe3O4 nanostructures are studied extensively for the use of enzymatic glucose sensor applications. However, reports on the non-enzymatic sensing performance of Fe3O4 for direct oxidation of glucose are rare. Therefore, in this work, a novel glassy carbon electrode modified with iron oxide/graphene nanocomposites (Fe3O4/graphene/GCE) was used for the non-enzymatic amperometric determination of glucose. The Fe3O4/graphene nanocomposite was first synthesised in alkaline aqueous solution through a simple chemical reduction process. The modified electrode was then studied for a non-enzymatic glucose sensing application in 0.1 M KNO3 supporting electrolyte (pH = 3.0). Under optimized conditions, the low detection limit of 0.18 mu M with a linear range from 50 mu M to 4.00 mM as well as good sensitivity (959.00 mu A mM(-1) cm(2)), stability and reproducibility have been obtained using the Fe3O4/graphene/GCE, thus, leading to a promising candidate for nonenzymatic glucose detection. The sensor was employed for the testing of glucose concentration in real blood samples.