• 文献标题:   Graphene quantum dots redefine nanobiomedicine
  • 文献类型:   Review
  • 作  者:   HENNA TK, PRAMOD K
  • 作者关键词:   graphene quantum dot, drug, photoluminescence, quenching, selfassembly, biosensing, bioimaging
  • 出版物名称:   MATERIALS SCIENCE ENGINEERING CMATERIALS FOR BIOLOGICAL APPLICATIONS
  • ISSN:   0928-4931 EI 1873-0191
  • 通讯作者地址:   Govt Med Coll
  • 被引频次:   7
  • DOI:   10.1016/j.msec.2020.110651
  • 出版年:   2020

▎ 摘  要

Carbon-based nanomaterials have established a prime position as drug delivery carriers. It is very interesting to see that a carbon nanostructure could be used as a drug too, instead of its regular application as a drug delivery carrier. In this aspect, graphene quantum dots (GQDs) are now in the spotlight. GQDs are one of the recent entrants to the list of carbon-based nanomaterials. They are now reported useful in Parkinson's and Alzheimer's diseases. Furthermore, antibacterial and anti-diabetic potentials of GQDs are now known. In addition, they are now widely evaluated for drug delivery application. They have good potential for drug delivery across the blood-brain barrier. Tumor-targeted drug delivery is also possible with GQDs. Their biosensing and bioimaging applications are also under extensive study. In this review, the therapeutic, drug delivery, biosensing and bioimaging applications of GQDs are described. It would be very interesting to speculate the future of GQDs and how this carbon nanomaterial influences the future of nanobiomedicine. It is presumed that drug-GQD duo would be the next generation strategy for many unresolved therapeutic hurdles.