• 文献标题:   Graphene nanoribbons: A promising nanomaterial for biomedical applications
  • 文献类型:   Review
  • 作  者:   JOHNSON AP, GANGADHARAPPA HV, PRAMOD K
  • 作者关键词:   graphene nanoribbon, photothermal therapy, surface modification, drug delivery, toxicity
  • 出版物名称:   JOURNAL OF CONTROLLED RELEASE
  • ISSN:   0168-3659 EI 1873-4995
  • 通讯作者地址:   JSS Acad Higher Educ Res
  • 被引频次:   0
  • DOI:   10.1016/j.jconrel.2020.06.034
  • 出版年:   2020

▎ 摘  要

Graphene nanoribbons (GNRs) are narrow lengthened strips of single-layer graphene. Among the graphene family of nanomaterials, GNRs are remarkable materials due to their attractive physical, chemical, electrical, mechanical, thermal, and optical properties. They have an ultra-high surface area. Graphene-oxide nanoribbons (GONRs), the oxygenated derivative of GNRs, offer more possibilities in the biomedicine due to their amphiphilic nature. Noncovalent and covalent modifications of these are possible for advanced biomedical applications. This review describes the properties, synthesis, surface modifications, and toxicities of GNRs, along with their biomedical applications. Their applications in drug delivery, anticancer therapy, sensing, antimicrobial therapy, imaging, gene therapy, photothermal therapy, management of spinal cord injury, bone regeneration, etc. are reviewed.