▎ 摘　　要

The commercial interbody fusion cage is generally based on rigid materials (e.g. Ti metal, PEEK plastic and so on), resulting in discomfort and limiting the movement of vertebration for human. A new soft and elastic polymer composite is prepared by self-exothermic esterification-crosslinking method for application in interbody fusion cage. It is mainly composed of bio-polymer (e.g. PVA and Chitosan), hydroxyapatite and graphene nanosheets. The interbody fusion cage is fabricated by 3D printing and mould process from bio-polymer composite. The interbody fusion cage does not only show high elastic modulus (ca. 246.5 MPa), but also exhibits good compression elastic deformation (more than 15%), enhancing comfort of human. Furthermore, the interbody fusion cage can produce Ca ions and shows grade 1 (few reactivity) of cytotoxicity, indicating good osteoconductivity and biocompatibility. The work demonstrates the practical application of present bio-polymer/graphene composite in interbody fusion cage with comfort.