• 文献标题:   Graphene oxide-enabled tandem signal amplification for sensitive SPRi immunoassay in serum
  • 文献类型:   Article
  • 作  者:   HU WH, HE GL, CHEN T, GUO CX, LU ZS, SELVARAJ JN, LIU Y, LI CM
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345 EI 1364-548X
  • 通讯作者地址:   Chinese Acad Agr Sci
  • 被引频次:   34
  • DOI:   10.1039/c3cc47933a
  • 出版年:   2014

▎ 摘  要

A tandem signal amplification using bioconjugated graphene oxide and subsequent silver catalytic deposition for surface plasmon resonance imaging (SPRi) to sensitively and specifically immunoassay tumor bio-markers in serum, achieving a limit of detection down to 100 pg mL(-1) with a broad dynamic range for alpha-Fetoprotein (AFP) is reported.