• 文献标题:   Electrochemical Detection of Norepinephrine in the Presence of Epinephrine, Uric Acid and Ascorbic Acid Using a Graphene-modified Electrode
  • 文献类型:   Article
  • 作  者:   MA XY, CHEN MF, LI X, PURUSHOTHAMAN A, LI FC
  • 作者关键词:   modified electrode, graphene, norepinephrine, reduction peak current
  • 出版物名称:   INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
  • ISSN:   1452-3981
  • 通讯作者地址:   Heze Univ
  • 被引频次:   21
  • DOI:  
  • 出版年:   2012

▎ 摘  要

A glassy carbon electrode was modified with graphene. In phosphate buffer solution, the modified electrode showed an excellent electrocatalytical effect on the oxidation of norepinephrine (NE). This was further used to determine NE in the presence of epinephrine, uric acid and ascorbic acid by cyclic voltammetry. The reduction peak current showed a linear relationship with the concentrations of NE in the range of 6.00x10(-7) to 1.20x10(-4) mol.L-1, with the detection limit of 4.00x10(-7) mol.L-1. The modified electrode can be used to selectively determine NE in the presence of epinephrine, uric acid and ascorbic acid by measuring reduction peak current in PBS pH 7.0. The method has high sensitivity, selectivity, stability, and has been successfully applied to analyzing injection samples of NE.