▎ 摘　　要

A rapid and sensitive, non-enzymatic electrochemical detection of hydrogen peroxide (H2O2) is of utmost importance for diagnosis and treatment of related diseases in clinical purpose. To meet this requirement, we report a simple and robust microwave-assisted synthetical route via prepared Gd2O3 nanoparticles decorated reduced graphene oxide nanocomposite (Gd2O3 NPs@RGO) modified electrode for non-enzymatic H2O2 detection. The composition and morphological formation were characterized by using XRD, FT-IR, XPS, FESEM, and HRTEM. The impedance and cyclic voltammetry exhibit tremendous electrocatalytic capability and superior performance toward H2O2 reduction. A sensitive and reproducible amperometric H2O2 sensor was fabricated which was able to detect concentration as low as 1.57 nM. The method worked well even in clinical and biological samples, which indicates the reliability of the method in real time analysis.