• 文献标题:   Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
  • 文献类型:   Article
  • 作  者:   QIU XJ, YOU XR, CHEN X, CHEN HL, DHINAKAR A, LIU SH, GUO ZY, WU J, LIU ZM
  • 作者关键词:   gold nanorod, graphene oxide, nearinfrared bioimaging, surfaceenhanced raman scattering
  • 出版物名称:   INTERNATIONAL JOURNAL OF NANOMEDICINE
  • ISSN:   1178-2013
  • 通讯作者地址:   South China Normal Univ
  • 被引频次:   10
  • DOI:   10.2147/IJN.S130648
  • 出版年:   2017

▎ 摘  要

The rapid development of near-infrared surface-enhanced Raman scattering (NIR SERS) imaging technology has attracted strong interest from scientists and clinicians due to its narrow spectral bandwidth, low background interference, and deep imaging depth. In this report, the graphene oxide (GO)-wrapped gold nanorods (GO@GNRs) were developed as a smart and robust nanoplatform for ultrafast NIR SERS bioimaging. The fabricated GO@ GNRs could efficiently load various NIR probes, and the in vitro evaluation indicated that the nanoplatform could exhibit a higher NIR SERS activity in comparison with traditional gold nanostructures. The GOs were prepared by directly pyrolyzing citric acid for greater convenience, and GO@ GNRs were fabricated via a facile synthesis strategy. Higher NIR SERS activity, facile synthesis method, excellent biocompatibility, and superb stability make the GO@ GNRs/probe complex promising nanoprobes for NIR SERS-based bioimaging applications.