• 文献标题:   Aptamer selection for fishing of palladium ion using graphene oxide-adsorbed nanoparticles
  • 文献类型:   Article
  • 作  者:   CHO YS, LEE EJ, LEE GH, HAH SS
  • 作者关键词:   aptamer, graphene oxide, adsorption, selex, palladium ion
  • 出版物名称:   BIOORGANIC MEDICINAL CHEMISTRY LETTERS
  • ISSN:   0960-894X EI 1464-3405
  • 通讯作者地址:   Kyung Hee Univ
  • 被引频次:   7
  • DOI:   10.1016/j.bmcl.2015.10.056
  • 出版年:   2015

▎ 摘  要

A new aptamer selection method using graphene oxide (GO)-adsorbed nanoparticles (GO-adsorbed NPs) was employed for specific fishing of palladium ion. High affinity ssDNA aptamers were isolated through 13 rounds of selection and the capacity of the selected DNA aptamers for palladium ion uptake was measured, clarifying that DNA01 exhibits the highest affinity to palladium ion with a dissociation constant (K-d) of 4.60 +/- 1.17 mu M. In addition, binding ability of DNA01 to palladium ion was verified against other metal ions, such as Li+, Cs+, Mg2+, and Pt2+. Results of the present study suggest that future modification of DNA01 may improve palladium ion-binding ability, leading to economic recovery of palladium from water solution. (C) 2015 Elsevier Ltd. All rights reserved.