▎ 摘　　要

Objectives: Oral prosthetic rehabilitation has been used for a long time to restore function and natural appearance; however, it is still one of the most challenging areas in dentistry due to its technical fabrication process and biological behavior. Considering the ad-vantages of additive manufacturing technology, this study introduced the feasibility of developing a 3D printed resin-based composition modified with graphene nanoplatelets (GNPs) to improve properties.Methods: Acrylate-based resin was impregnated with different concentrations of GNPs (0.0-0.25 wt%), and then different aspects such as mechanical, physical, biological and antimicrobial were analyzed to evaluate the effectiveness. TEM and SEM were used to characterize GNPs and their existence within the resin. Surface topography and roughness were evaluated using AFM. The degree of conversion and composition were confirmed by FTIR. Mechanical properties were detected using bending strength, microhardness and nanoindentation. Biocompatibility and antimicrobial activities were assessed with oral fi-broblast and Candida albicans (C. albicans), respectively. In addition, most of the mea-surements were performed repeatedly after 3 months of storage in artificial saliva to evaluate performance.Results: GNPs improved strength significantly at low concentrations