• 文献标题:   Hall effect biosensors with ultraclean graphene film for improved sensitivity of label-free DNA detection
  • 文献类型:   Article
  • 作  者:   LOAN PTK, WU DQ, YE C, LI XQ, TRA VT, WEI QP, FU L, YU AM, LI LJ, LIN CT
  • 作者关键词:   graphene biosensor, dna hybridization, hall effect measurement, ultraclean surface, goldtransfer method
  • 出版物名称:   BIOSENSORS BIOELECTRONICS
  • ISSN:   0956-5663 EI 1873-4235
  • 通讯作者地址:   Chinese Acad Sci
  • 被引频次:   25
  • DOI:   10.1016/j.bios.2017.07.045
  • 出版年:   2018

▎ 摘  要

The quality of graphene strongly affects the performance of graphene-based biosensors which are highly demanded for the sensitive and selective detection of biomolecules, such as DNA. This work reported a novel transfer process for preparing a residue-free graphene film using a thin gold supporting layer. A Hall effect device made of this gold-transferred graphene was demonstrated to significantly enhance the sensitivity (approximate to 5 times) for hybridization detection, with a linear detection range of 1 pM to 100 nM for DNA target. Our findings provide an efficient method to boost the sensitivity of graphene-based biosensors for DNA recognition.