• 文献标题:   A unique turn-off fluorescent strategy for sensing dopamine based on formed polydopamine (pDA) using graphene quantum dots (GQDs) as fluorescent probe
  • 文献类型:   Article
  • 作  者:   WENG SH, LIANG D, QIU HZ, LIU ZG, LIN Z, ZHENG ZF, LIU AL, CHEN W, LIN XH
  • 作者关键词:   dopamine detection, graphene quantum dot, fluorescent sensor, polydopamine, serum
  • 出版物名称:   SENSORS ACTUATORS BCHEMICAL
  • ISSN:   0925-4005
  • 通讯作者地址:   476 Hosp PLA
  • 被引频次:   46
  • DOI:   10.1016/j.snb.2015.06.093
  • 出版年:   2015

▎ 摘  要

A rapid, facile fluorescence sensing strategy was developed for dopamine (DA) detection based on poly-dopamine (pDA) formed on the surface of graphene quantum dots (GQDs). The prepared GQDs were strongly luminescent because of the aromatic planar structure. DA could self-polymerize to pDA and snap to the surface of GQDs to form a thin film in alkaline environment, leading to quenching of fluorescence due to fluorescence resonance energy transfer (FRET). With the optimized conditions, the analytical performance illustrated high sensitivity, selectivity in a wide linear range with a detection limit of 8 nM. In addition, the unique method was successfully applied for DA injection test with satisfactory labeled amount. Finally, the proposed strategy was applied for DA detection in serum, wherein accurate results were obtained. (C) 2015 Elsevier B.V. All rights reserved.