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  • 文献标题:   Aptamer and graphene-based electrochemical biosensor for dopamine determination with high sensitivity and selectivity
  • 文献类型:   Article
  • 作　　者:   JIAO LY, LU GJ, ZHANG CX, YUAN Y, WANG JX, ZHANG QM, LI PF
  • 作者关键词:   biosensor, disease, electrochemical sensor, molecular biophysic, molecular configuration, nanostructured material, neurophysiology, rna, sensitivity, sheet material, graphene, nanosensor, c, graphene nanosheet, electronic propertie, rna aptamer, specihc recognition, costeffective electrochemical method, convenient electrochemical method, dopamine detection, neurodegenerative disease, psychiatric disease, dopamine metabolism, neurotransmitter, sensitivity, dopamine determination, graphenebased electrochemical biosensor, aptamerbased electrochemical biosensor
  • 出版物名称:   MICRO NANO LETTERS
  • ISSN:   1750-0443
  • 通讯作者地址:   XinXiang Med Univ
  • 被引频次:   10
  • DOI:   10.1049/mnl.2013.0626
  • 出版年:   2013

▎ 摘　　要

Dopamine is a kind of neurotransmitter. The abnormalities in dopamine metabolism may lead to various psychiatric and neurodegenerative diseases. Thus, fast and accurate detection of dopamine is urgently needed. Presented in this Letter is a convenient and cost-effective electrochemical method for the detection of dopamine based on aptamer and graphene. The specific recognition between dopamine and the RNA aptamer allows high selectivity, and the excellent electronic properties of graphene nanosheets ensure the high sensitivity of this biosensor.