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  • 文献标题:   Preparation of Amphiphilic Chitosan-Graphene Oxide-Cellulose Nanocrystalline Composite Hydrogels and Their Biocompatibility and Antibacterial Properties
  • 文献类型:   Article
  • 作　　者:   YANG MC, TSENG YQ, LIU KH, CHENG YW, CHEN WT, CHEN WT, HSIAO CW, YUNG MC, HSU CC, LIU TY
  • 作者关键词:   amphiphatic chitosan, cellulose nanocrystal, graphene oxide, nanocomposite hydrogel, antibacterial ability
  • 出版物名称:   APPLIED SCIENCESBASEL
  • ISSN:  
  • 通讯作者地址:   Ming Chi Univ Technol
  • 被引频次:   5
  • DOI:   10.3390/app9153051
  • 出版年:   2019

▎ 摘　　要

Environmental-friendly nanocomposite hydrogels of carboxymethyl-hexanoyl chitosan (CHC), graphene oxide (GO) and cellulose nanocrystals (CNCs) were combined to produce a bio-hydrogel with great biocompatibility and antibacterial ability. The size of the GO nanosheets was about 200-500 nm, and the CNCs had a length of 100-200 nm and a width of 10-20 nm, as shown by transmission electron microscopy (TEM). X-ray photoelectron spectroscopy (XPS) was utilized for the analysis of the oxygen functional groups of GO. The homogeneous dispersion of the CHC/GO/CNC nanocomposite hydrogel showed significantly higher water absorption capacity and water retention capability. In addition, inhibition of a variety of microorganisms (gram-negative and gram-positive bacteria and fungi) by the introduction of the CHC/GO/CNC nanocomposite hydrogel demonstrated that there is a great opportunity to use it in the bio-medical field, such as for plastic masks and wound dressings.