• 文献标题:   Nitric oxide-generating L-cysteine-grafted graphene film as a blood-contacting biomaterial
  • 文献类型:   Article
  • 作  者:   DU Z, DOU RX, ZU MA, LIU XY, YIN WY, ZHAO YL, CHEN JB, YAN L, GU ZJ
  • 作者关键词:  
  • 出版物名称:   BIOMATERIALS SCIENCE
  • ISSN:   2047-4830 EI 2047-4849
  • 通讯作者地址:   Zhengzhou Univ
  • 被引频次:   9
  • DOI:   10.1039/c6bm00074f
  • 出版年:   2016

▎ 摘  要

By using polyethylenimine molecules as the linker, L-cysteine was immobilized onto graphene nanosheets, endowing the biocompatible L-cysteine-functionalized graphene film with the ability for catalytic decomposition of exogenous or endogenous donors to generate nitric oxide, and thus inhibiting the platelet activation and aggregation and reducing platelet adhesion.