▎ 摘　　要

In recent years, graphene, the two-dimensional closely packed honeycomb carbon lattice, has been attracting much attention in the field of electrochemistry due to its intrinsic properties and merits. Efforts to create novel graphene based electrochemical biosensors have led to the establishment of effective strategies for diverse bioassays, from simple molecules to complex biotargets. In this Feature Article, we provide an overview of electrochemical biosensing with graphene related materials, and discuss the role of graphene in different sensing protocols.