• 文献标题:   Electro-stimulated release from a reduced graphene oxide composite hydrogel
  • 文献类型:   Article
  • 作  者:   MAC KENNA N, CALVERT P, MORRIN A, WALLACEC GG, MOULTON SE
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF MATERIALS CHEMISTRY B
  • ISSN:   2050-750X EI 2050-7518
  • 通讯作者地址:   Univ Wollongong
  • 被引频次:   21
  • DOI:   10.1039/c5tb00050e
  • 出版年:   2015

▎ 摘  要

Electro-stimulated release was established using a novel, electro-conductive hydrogel system comprising Jeffamine polyetheramine and polyethylene glycol diglycidyl ether (PEGDGE) that was composited with reduced graphene oxide (rGO). The swelling response, morphology, mechanical and electrochemical properties of the composite hydrogel were investigated. Enhanced mechanical and electrical properties were observed with increased rGO content. Passive and electro-stimulated release of methyl orange (MO) from these gels was examined. A significant reduction in passive release of the dye was observed by incorporating rGO. Upon electrical stimulation, the release rate and dosage could be tuned through variation of the % w/w rGO, as well as the polarity and amplitude of the applied electric potential. A high level of control and flexibility was achieved demonstrating the applicability of this system for localised drug delivery applications.