• 文献标题:   Electrochemical determination of adenine using a glassy carbon electrode modified with graphene oxide and polyaniline
  • 文献类型:   Article
  • 作  者:   SHARMA V, HYNEK D, TRNKOVA L, HEMZAL D, MARIK M, KIZEK R, HUBALEK J
  • 作者关键词:   nanocomposite, sensor, cyclic voltammetry, differential pulse voltammetry, scanning electron microscopy, raman spectroscopy
  • 出版物名称:   MICROCHIMICA ACTA
  • ISSN:   0026-3672 EI 1436-5073
  • 通讯作者地址:   Masaryk Univ
  • 被引频次:   10
  • DOI:   10.1007/s00604-015-1740-0
  • 出版年:   2016

▎ 摘  要

The electrochemical behavior of adenine at a glassy carbon electrode (GCE) modified with a nanocomposite consisting of graphene oxide and polyaniline was investigated by cyclic voltammetry and differential pulse voltammetry. The nanocomposite was synthesized by polymerization and characterized by Raman and UV-vis spectroscopy, and its morphology was examined by scanning electron microscopy. Adenine is oxidized at the modified GCE at a working potential of 1.2 V (vs. Ag/AgCl) and gives a current density of approximately 2.64 nA.cm(-2), which is distinctly increased compared to the 0.57 nA.cm(-2) of a bare electrode. Peak current and adenine concentration are linearly related to each other in the range from 0.5 mu M to 20 mu M. The modified GCE exhibits acceptable analytical performance, with a detection limit of 72 nM and a limit of quantification of 240 nM. It is excellently reproducible, stable, and fabrication is simple.