• 文献标题:   Detection of Neurotransmitters by Three-Dimensional Laser-Scribed Graphene Grass Electrodes
  • 文献类型:   Article
  • 作  者:   XU GY, JARJES ZA, WANG HW, PHILLIPS ARJ, KILMARTIN PA, TRAVASSEJDIC J
  • 作者关键词:   laser scribed graphene gras, electrochemical sensor, dopamine, epinephrine, norepinephrine, ascorbic acid, uric acid
  • 出版物名称:   ACS APPLIED MATERIALS INTERFACES
  • ISSN:   1944-8244
  • 通讯作者地址:   Univ Auckland
  • 被引频次:   4
  • DOI:   10.1021/acsami.8b16692
  • 出版年:   2018

▎ 摘  要

Carbon nanomaterials possess superb properties and have contributed considerably to the advancement of integrated point-of-care chemical and biological sensing devices. Graphene has been widely researched as a signal transducing and sensing material. Here, a grass-like laser-scribed graphene (LSG) was synthesized by direct laser induction on common polyimide plastics. The resulting LSG grass was employed as a disposable electrochemical sensor for the detection of three neurotransmitters, dopamine (DA), epinephrine (EP), and norepinephrine (NE), and in the presence of uric acid and ascorbic acid as potential interferants, using differential pulse voltammetry and cyclic voltammetry. The LSG grass sensor achieved sensitivities of 0.243, 0.067, and 0.110 mu A mu M-1 for DA, EP, and NE, respectively, whereas the limits of detection were 0.43, 1.1, and 1.3 mu M, respectively. The selectivity of LSG grass was excellent for competing biomarkers with high structural similarity (EP vs NE and EP vs DA). The exceptional performance of LSG grass for DA, EP, and NE detection holds a promising future for carbon nanomaterial sensors with unique surface morphologies.