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  • 文献标题:   Electrochemically driven drug metabolism via a CYP1A2-UGT1A10 bienzyme confined in a graphene nano-cage
  • 文献类型:   Article
  • 作　　者:   LU JS, ZHANG YJ, LI HN, YU JC, LIU SQ
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345 EI 1364-548X
  • 通讯作者地址:   Southeast Univ
  • 被引频次:   8
  • DOI:   10.1039/c4cc06200k
  • 出版年:   2014

▎ 摘　　要

A graphene nano-cage with regulatable space for the assembly of a cytochrome P450 1A2-UDP-glucuronosyltransferase 1A10 bienzyme complex has been constructed via a click reaction, and successfully used to study drug sequential metabolism using an electrochemically-driven method.