▎ 摘　　要

In this work, the application of graphene quantum dots (GQD) modified screen printed electrode (SPE) (GQD/SPE) in the electrochemical detection of acetylcholine is presented. The modification of the SPE with graphene quantum dots resulted in increased oxidation current of acetylcholine oxidation when compared to that obtained from bare SPE. The linear concentration range was between 1.0 and 800.0 mu M and limit of detection was calculated to be 0.3 mu M. The GQD/SPE sensor was used for the quantitative analysis of acetylcholine in acetylcholine injection and urine samples. The sufficiently good recoveries and low standard deviations reflect the high accuracy of developed method.