• 文献标题:   DNA Translocation through Graphene Nanopores
  • 文献类型:   Article
  • 作  者:   MERCHANT CA, HEALY K, WANUNU M, RAY V, PETERMAN N, BARTEL J, FISCHBEIN MD, VENTA K, LUO ZT, JOHNSON ATC, DRNDIC M
  • 作者关键词:   dna sequencing, atomic layer deposition, single molecule, nanopore
  • 出版物名称:   NANO LETTERS
  • ISSN:   1530-6984 EI 1530-6992
  • 通讯作者地址:   Univ Penn
  • 被引频次:   579
  • DOI:   10.1021/nl101046t
  • 出版年:   2010

▎ 摘  要

We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, we observe larger blocked currents than for traditional solid-state nanopores. However, ionic current noise levels are several orders of magnitude larger than those for silicon nitride nanopores. These fluctuations are reduced with the atomic-layer deposition of 15 nm of titanium dioxide over the device. Unlike traditional solid-state nanopore materials that are insulating, graphene is an excellent electrical conductor. Use of graphene as a membrane material opens the door to a new class of nanopore devices in which electronic sensing and control are performed directly at the pore.