▎ 摘　　要

The purpose of this laboratory study was to formulate and characterize the graphene oxide-poly(methyl methacrylate) resin composite with an intended use as bone cement. Graphene oxide was fabricated through ultrasonication route. The autopolymerization resin (Eco Cryl Cold, Protechno, Vilamalla Girona, Spain) was used to prepare the specimens of required dimensions for different testing parameters. The control group (C-group) was prepared as such. However, for GO1-group, 0.024wt/wt.-% of graphene oxide was incorporated in a resin matrix and GO2-group was a composite with 0.048wt/wt.-% of graphene oxide in a resin matrix. TEM examination of graphene oxide sheets demonstrated them in the range of approximate to 500nm to approximate to 2 mu m. The mechanical properties were characterized using three-point bending and wear resistance, while material properties were assessed through transmission electron microscope, scanning electron microscopy, Fourier-transform infrared spectroscopy, Raman spectroscopy, X-ray diffraction, differential scanning calorimetry and thermo-gravimetric analysis. The results suggest that 0.024wt/wt.-% and 0.048wt/wt.-% of loading of GO have no effect on the physiochemical characteristics. However, thermal characteristics might slightly be improved. According to the analysis of variance results (p<0.05, n=5), wear resistance and bending strength of both GO1 and GO2 groups significantly improved compared to C-group. The bending strength of GO2 improved to 87.0 +/- 7.2MPa from 65.9 +/- 11.5MPa of C-group. Scanning electron microscopy examination of the fractured surface demonstrated granule like structure where the graphene oxide sheets might be covered inside PMMA. The use of GO-PMMA composites favorably enhances the mechanical properties of bone cement.