▎ 摘　　要

A reduced graphene oxide (RGO) supported electropolymerised copper coordinated aminoacid (Cu-poly(Ala)) was deposited on a glassy carbon electrode (GCE) by a two-step process and its application as a sensor is demonstrated herein. The prepared nanocomposite presented a novel way for the design of an electrochemical sensor by incorporating the fascinating characteristics of amino acid alanine as the molecular host providing cavities and Cu2+ as the active centre generating a platform for electrochemical deposition of RGO. The sensor was able to detect both phenolic as well as tertiary amine group of morphine (MO). A lowering of potentials by 270 mV and 145 mV compared to bare GCE was monitored, which is much lower than available reports. An enhanced rate constant of the order of 3.5 x 10(5) mol(-1) L s(-1) was obtained. This novel sensing platform for MO produced a very low detection limit of 47 nM with a very good linear dynamic range 50 nm to 80 mu M. The sensor displayed good anti interference ability, stability and was successfully applied to real sample analysis. (C) 2019 Elsevier B.V. All rights reserved.