▎ 摘　　要

A new rare earth oxide of Er2O3 was employed for the construction of glucose biosensor. Er2O3 was mixed with graphene oxide (GO) to form the supported matrix for immobilization of glucose oxidase (GOD) onto the glassy carbon electrode (GCE). The nanomaterials of Er2O3 and GO were firstly synthesized and characterized by SEM, XRD. The fabrication process for the biosensor was monitored by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The presence of Er2O3 could effectively maintain the bioactivity of GOD and enhance the electron transfer rate. The prepared biosensor showed a pair of distinct and well-defined redox peaks, indicating the fast direct electron transfer (DET) rate between the redox-active site of GOD and GCE, which could be attributed to the synergistic effect of the GO/Er2O3 nanocomposite. When employed to the electrocatalytic detection of glucose, the CV response of the prepared biosensor decreased against the concentrations of glucose. The calibration curve corresponding to the CV response was linear against the concentrations of glucose ranging from 1 to 10 mmol.L-1. Moreover, the biosensor showed good stability and reproducibility.