▎ 摘 要
A simple and straightforward one-pot three-component synthesis of 2H-indazoles through copper-catalyzed consecutive condensation, C-N and N-N bond formations of easily accessible starting materials under ligand-free conditions is described. In this protocol, treatment of substituted 2-bromobenzaldehydes, structurally diverse amines, and [bmim]N-3 in the presence of Cu/aminoclay/reduced graphene oxide nanohybrid (Cu/AC/r-GO nanohybrid) as an efficient heterogeneous catalyst affords the corresponding 2H-indazoles in good to excellent yields. The influence of effective parameters on the efficient progress of the reaction was studied. The Cu/AC/r-GO nanohybrid is a stable and inexpensive catalyst that could be simply prepared, recovered, and reused for several reaction runs with no significant decrease in its reactivity.