▎ 摘　　要

Skin is the largest organ of the human body and can perceive and respond to complex environmental stimuli. As a 2D atomic layer of sp2 over line hybridized carbon arranged in a hexagonal network, graphene is regarded as a promising material for nanoelectronics owing to its high crystallinity and interesting semimetal electronic properties. In addition, graphene has extremely strong perception ability and high selectivity for different stimuli, and graphene over line based materials have been widely used as key perceiving materials of artificial flexible sensors to imitate the flexibility and stretchability of human skin, which is one of the most promising wearable and sensing materials for potential commercialization. This paper first introduces the main working mechanisms of piezoresistive type, capacitive type, piezoelectric type and transistor type, as well as the key performance evaluation parameters such as sensitivity, detection range, response speed and so on of sensors. At the same time, the advantages and synthesis methods of graphene materials are also briefly summarized. In conjunction of our recent research works of graphene over line based composite materials made up of graphene and polyaniline, Ag nanoparticles, carbon nanotubes, Ni(OH) 2( II) and quantum dots for flexible sensors, this paper then reviews the applications of graphene over line based single function flexible sensors in detecting pressure, strain, temperature, humidity, chemical molecules, biomolecules, gas and other fields, as well as several graphene over line based multifunctional flexible sensors. Finally, the future development of graphene over line based flexible sensors is prospected.