▎ 摘　　要

A graphene-L-cystine modified glassy carbon electrode (GR-L-CysS/GCE) has been prepared. The electrochemical behavior of isoprenaline hydrochloride at the modified electrode has been studied. In 0.2 mol/L Na2HPO4-citric acid (pH 7. 4) buffer, GR-L-CysS/GCE exhibited excellent catalytic and enhancement effect on the electrochemical oxidation of isoprenaline hydrochloride, and the oxidation peak current increased ca. 13 times compared with that at bare GCE. The measurement parameters were optimized. Under the optimal conditions, isoprenaline hydrochloride concentration was linear with peak current in the range of 4.0 X 10(-6)-1. 6 X 10(-4) mol/L (R=0. 9977), and the detection limit was 8. 4 X 10(-7) mol/L(S/N=3). The mechanism investigation showed that the reaction of isoprenaline hydrochloride at the modified electrode was a process with one-proton and one-electron transfer, and the coefficient of electron transfer alpha is 0. 4635. This method was successfully used in the determination of isoprenaline hydrochloride in injection with the recovery between 94. 9%-102. 9%.