• 文献标题:   Construction of chitin/graphene oxide hybrid hydrogels
  • 文献类型:   Article
  • 作  者:   GUO Y, DUAN B, CUI L, ZHU P
  • 作者关键词:   chitin, graphene oxide go, hybrid hydrogel, mechanical propertie, biocompatibility
  • 出版物名称:   CELLULOSE
  • ISSN:   0969-0239 EI 1572-882X
  • 通讯作者地址:   Wuhan Text Univ
  • 被引频次:   20
  • DOI:   10.1007/s10570-015-0630-2
  • 出版年:   2015

▎ 摘  要

Graphene oxide (GO), an excellent nanofiller, was incorporated into chitin to construct chitin/GO hybrid hydrogels by cross-linking with epichlorohydrin. The structure of the hybrid hydrogels was investigated by Fourier-transform infrared (FT-IR) spectroscopy, wide-angle X-ray diffraction, thermogravimetric analysis, and scanning electron microscopy. The results revealed that the hybrid hydrogels possessed a layered porous structurewith bi-crosslinked networks, which played an important role in improving their mechanical properties. Compared with pure chitin hydrogels, an increase of 24.7 and 262.7 % in strain and compressive strength, respectively, was achieved with addition of 3.2 wt% GO. Incorporation of this amount of GO in a hybrid hydrogel did not affect the toxicity of chitin towards L02 cells, suggesting good biocompatibility. All these results suggest that chitin/GO hydrogels have potential applications in the field of tissue engineering.