▎ 摘　　要

In present work we report application of bismuth (Ill) oxide (Bi2O3) decorated graphene nanoribbons (GNR) composite for modification of screen printed electrode, and use of resulting modified screen-printed electrode (SPCE/GNR/Bi2O3) as a disposable glucose biosensor. The composite was synthesized by use of co-precipitation method followed by ultra-sonication. After characterization, the material was applied on the surface of the screen-printed electrode in a 'drop casting' fashion. Glucose oxidase (GO(x)) was added to the modified surface and finally covered by Nafion film. Resulting biosensor electrode (SPCE/GNR/Bi2O3/GO(x)/Naf) shows excellent performance toward glucose detection, with working linear range from 0.28 to 1.70 mM and detection limit of 0.07 mM. Prepared biosensor was applied for the estimation of glucose level in standard honey samples with declared glucose level, in order to validate the methods (PT scheme). Obtained results are indicating excellent stability, reproducibility, accuracy and precision of the method for the determination of glucose in such samples with negligible matrix effect. Developed biosensor showed high precision, accuracy and selectivity even when employed for determination of glucose content in blood serum and urine samples. Proposed biosensor construction shows promising results and can be considered as stabile and reproducible tool for detection and quantification of glucose in investigated samples. (C) 2019 Elsevier B.V. All rights reserved.