• 文献标题:   Cuprous oxide anchored Reduced Graphene oxide ceramic nanocomposite using Tagetes erecta flower extract and evaluation of its antibacterial activity and cytotoxicity
  • 文献类型:   Article
  • 作  者:   RANI MN, MURTHY M, SHREE NS, ANANDA S, YOGESH S, DINESH R
  • 作者关键词:   reduced graphene oxide, rgocu2o nanocomposite, green synthesi, antibacterial activity, cytotoxicity
  • 出版物名称:   CERAMICS INTERNATIONAL
  • ISSN:   0272-8842 EI 1873-3956
  • 通讯作者地址:   Visvesvaraya Technol Univ
  • 被引频次:   1
  • DOI:   10.1016/j.ceramint.2019.04.195
  • 出版年:   2019

▎ 摘  要

Cuprous oxide anchored Reduced Graphene oxide (RGO) ceramic nanocomposite was pepared by a simple phytochemical assisted route using Tagetes erecta (Marigold) flower extract. The simultaneous reduction of graphene oxide (GO) and formation of Cu2O nanoparticles on RGO was achieved using Tagetes erecta extract. The PXRD results confirm the formation of Cu2O nanoparticles on the RGO sheet with an average particle size of about 22 nm. The RGO-Cu2O hybrid nanomaterial showed better antibacterial activity when compared to RGO alone studied against both gram-negative and gram-positive bacteria. Cytotoxicity studies revealed the significant concentration-dependent growth inhibition of SCC-9 oral cancer cells with IC50 values 442.3 and 157.2 mu g/ml, respectively, for RGO and RGO-Cu2O nanocomposites. The study successfully demonstrates a simple and eco-friendly method for the synthesis of efficient RGO-Cu2O ceramic nanocomposite using synthetic green approach.