• 文献标题:   Non-enzymatic electronic detection of glucose using aminophenylboronic acid functionalized reduced graphene oxide
  • 文献类型:   Article
  • 作  者:   VASU KS, SRIDEVI S, SAMPATH S, SOOD AK
  • 作者关键词:   glucose, aminophenylboronic acid, graphene oxide, field effect transistor, nonenzymatic detection
  • 出版物名称:   SENSORS ACTUATORS BCHEMICAL
  • ISSN:   0925-4005
  • 通讯作者地址:   Indian Inst Sci
  • 被引频次:   10
  • DOI:   10.1016/j.snb.2015.07.101
  • 出版年:   2015

▎ 摘  要

We report the non-enzymatic electronic detection of glucose using field effect transistor (FET) devices made of aminophenylboronic acid (APBA) functionalized reduced graphene oxide (RGO). Detection of glucose molecules was carried out over a wide dynamic range of concentration varying from 100 pM to 100 mM with a detection limit of similar to 2 nM using both covalently and non-covalently functionalized APBA-RGO complex. The normalized change in electrical conductance data shows that the FET devices made of non-covalently functionalized APBA-RGO complex (nc-APBA-RGO) exhibited a linear response to glucose aqueous solution of concentrations varying from 1 nM to 10 mM and showed 4 times enhanced sensitivity over the devices made of covalently functionalized APBA-RGO complex (c-APBA-RGO). Specificity of APBA-RGO complex to glucose is confirmed from the observation of negligible change in electrical conductance after exposure to 0.1 mM of lactose and other interfering factors. (C) 2015 Elsevier B.V. All rights reserved.