▎ 摘 要
In the present work a novel multifunctional drug nanocarrier was prepared. Polyglycerol-g-polycaprolactone was grafted on Mesoporous silica-coated magnetic graphene oxide. Doxorubicin, as anticancer drug, was loaded on this carrier. The in vitro drug release showed the controlled pH responsive behavior. At the endosomal pH (pH 5.5) the amount of drug release enhanced. This nanocarrier would have potential application in the tumor therapy owing to its biodegradability, controlled release and pH responsive behavior. (C) 2015 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.