• 文献标题:   Generation of Cellular Micropatterns on a Single- Layered Graphene Film
  • 文献类型:   Article
  • 作  者:   HONG D, BAE K, YOO S, KANG K, JANG B, KIM J, KIM S, JEON S, NAM Y, KIM YG, CHOI IS
  • 作者关键词:   aryl azide, cell, graphene, micropattern, surfaceinitiated polymerization
  • 出版物名称:   MACROMOLECULAR BIOSCIENCE
  • ISSN:   1616-5187 EI 1616-5195
  • 通讯作者地址:   Korea Adv Inst Sci Technol
  • 被引频次:   11
  • DOI:   10.1002/mabi.201300346
  • 出版年:   2014

▎ 摘  要

Micropatterns of fibroblast and hippocampal neurons are generated on a single-layered graphene substrate. A large-area (1cmx1cm) graphene film on Si/SiO2 is functionalized by surface-initiated ATRP of non-biofouling oligo(ethylene glycol) methacrylate, after grafting of the polymerization initiator bearing -bromoisobutylate via photoreaction of the perfluorophenyl azide group. The microcontact printing-assisted spatio-selective reaction, after chemical activation of the terminal hydroxyl group of oligo(ethylene glycol) in the polymeric film, is utilized to generate the patterns of fibroblast and hippocampal neurons.