• 文献标题:   Reduced Graphene Oxide Functionalized with a Luminescent Rare-Earth Complex for the Tracking and Photothermal Killing of Drug-Resistant Bacteria
  • 文献类型:   Article
  • 作  者:   YANG XJ, LI ZH, JU EG, REN JS, QU XG
  • 作者关键词:   imaging, luminescent complexe, rareearth complexe, photothermal killing, reduced graphene oxide
  • 出版物名称:   CHEMISTRYA EUROPEAN JOURNAL
  • ISSN:   0947-6539 EI 1521-3765
  • 通讯作者地址:   Acad Sinica
  • 被引频次:   40
  • DOI:   10.1002/chem.201303964
  • 出版年:   2014

▎ 摘  要

An antibacterial platform based on multifunctional reduced graphene oxide (rGO) that is responsive to near-infrared (NIR) light has been constructed. By introducing a luminescent Eu3+ complex and vancomycin for bacteria tracking into one system, this platform could specifically recognize and light up bacteria. Antibacterial activity of this nanoscale construction under NIR illumination was investigated. Upon illumination with NIR light, this nanoscale architecture generates great heat locally, resulting in the death of drug-resistant bacteria. These results indicate that the ability of this nanoscale platform to kill drug-resistant bacteria has great potential for clinical pathogenic bacteria diagnosis and treatment.