• 文献标题:   Using Graphene Oxide High Near-Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
  • 文献类型:   Article
  • 作  者:   LI M, YANG XJ, REN JS, QU KG, QU XG
  • 作者关键词:   alzheimer s disease, amyloid, graphene, nanomaterial, phototherapy
  • 出版物名称:   ADVANCED MATERIALS
  • ISSN:   0935-9648 EI 1521-4095
  • 通讯作者地址:   Chinese Acad Sci
  • 被引频次:   298
  • DOI:   10.1002/adma.201104864
  • 出版年:   2012

▎ 摘  要

A novel strategy to dissociate amyloid aggregation is presented, using localised heat generation from a clinically used amyloid staining dye, thioflavin-S (ThS)modified graphene oxide (GO) under NIR laser irradiation. Compared to traditional chemotherapies, photothermal therapy shows reduced side effects and improved selectivity and safety.