▎ 摘　　要

The separation of racemates remains a great challenge as they are enantiomers with similar chemical structures and physicochemical properties in achiral environments. Recently, graphene oxide (GO) based membranes modified with various chiral selectors had been proved to allow for both high permeation flux and enantioselectivity. Herein, mono(6-amino-6-deoxy)-beta-cyclodextrin (f-CD) was selected to serve as chiral selector in GObased membranes for separating racemates, since it potentially forms specific inclusion complexes with guests. Results show that fl-CD displays a much stronger enantioselective affinity toward L-enantiomer than D-enantiomer, so that such fl-CD modified GO membrane (fl-CD-GOM) exhibits a retarded transport mechanism, having exceptional enantioselectivities with the enantiomeric excess value of nearly 100%. Moreover, fl-CD-GOMs are 12 orders of magnitude higher in flux than traditional enantioseparation membranes. These findings demonstrate that fl-CD-GOMs could provide new opportunities for improving enantioseparation performances with both high permeability and high permselectivity and for the large-scale production of various enantiomers.