• 文献标题:   Copper/Cuprous Oxide Nanoparticles Decorated Reduced Graphene Oxide Sheets Based Platform for Bio-Electrochemical Sensing of Dopamine
  • 文献类型:   Article
  • 作  者:   DEVNANI H, RASHID N, INGOLE PP
  • 作者关键词:   copper/cuprous oxide, dopamine, electrocatalytic sensing, nanocomposite, sonochemical synthesi, voltammetry
  • 出版物名称:   CHEMISTRYSELECT
  • ISSN:   2365-6549
  • 通讯作者地址:   Indian Inst Technol Delhi
  • 被引频次:   5
  • DOI:   10.1002/slct.201803233
  • 出版年:   2019

▎ 摘  要

A rudimentary simple sonochemical approach has been employed for the synthesis of copper/cuprous oxide nanoparticles (Cu/Cu2O NPs) decorated graphene oxide (GO) sheets. Simply, an aqueous dispersion of GO was sonochemically treated with Cu/Cu2O NPs as obtained through a simple electrochemical dissolution method to get the Cu/Cu2O/rGO nanocomposite. The decoration of Cu/Cu2O NPs on GO sheets resulted in the excellent sensing activity of Cu/Cu2O/rGO nanocomposite towards dopamine in the pharmaceutical formulation at the electrode interface due to enhanced electron mobility in GO sheet and high catalytic activity of Cu/Cu2O NPs. The comparison has been laid out based on various characterization techniques viz. powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infra-red (FTIR) spectroscopy and Raman spectroscopy. The fabricated sensor depicted high sensitivity of 0.806 mu A/mu M for dopamine in a broad linear range of 0.25 -17 mu M. Moreover, the remarkable detection limit of 2.6 nM was found for dopamine, and the developed sensor exhibited a wide separation ca. 140 mV between the respective detection peaks of dopamine and uric acid, which is a major interferent in the analysis of dopamine.