• 文献标题:   Ionic Liquids With Wafer-Scalable Graphene Sensors for Biological Detection
  • 文献类型:   Article, Proceedings Paper
  • 作  者:   MIKI H, ISOBAYASHI A, SAITO T, SUGIZAKI Y
  • 作者关键词:   ionic liquid, graphene, biosensor, biotin, streptavidin, urease
  • 出版物名称:   IEEE TRANSACTIONS ON NANOBIOSCIENCE
  • ISSN:   1536-1241 EI 1558-2639
  • 通讯作者地址:   Toshiba Co Ltd
  • 被引频次:   0
  • DOI:   10.1109/TNB.2019.2905286
  • 出版年:   2019

▎ 摘  要

Ionic liquids, known as non-volatile solvents, have potential for realizing microanalysis with a minute quantity of sample. Here, in this paper, we report the measurement of the Id-Vg characteristics during the enzymatic catalytic reactions and streptavidin-biotin binding in ionic liquids by using the graphene FET sensors we fabricated, and successfully monitored the biological reactions in much smaller amount of solvents. Thesefindings suggest the possibility of ionic liquids for application in bio-microanalysis with high sensitivity.