• 文献标题:   A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky end
  • 文献类型:   Article
  • 作  者:   HUANG J, YANG XH, HE XX, WANG KM, HE Y, QUAN K
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345
  • 通讯作者地址:   Hunan Univ
  • 被引频次:   16
  • DOI:   10.1039/c3cc45307c
  • 出版年:   2013

▎ 摘  要

Here we report a new strategy for designing a graphene oxide (GO)-quenched dye-labeled DNA hairpin probe by utilizing the sticky end adsorbed onto the GO surface. Only introduction of target DNA can alter the orientation of the sticky end, causing the dye to move apart from the GO surface, resulting in fluorescence restoration.